ACTICHROME® TFPI, activity assay, 100 tests

A three stage chromogenic assay which measures active Tissue Factor Pathway Inhibitor (TFPI) in plasma where TFPI exhibits an inhibitory effect on the tissue factor/fVIIa complex (TF/fVIIa).After incubation of test samples with TF/fVIIa and fX, the residual activity of the TF/fVIIa complex is measured using SPECTROZYME® fXa, a highly specific fXa chromogenic substrate. The TFPI activity present in the sample is interpolated from a standard curve constructed using known TFPI activity levels. The assay may be performed in either end-point or kinetic mode.For Research Use Only