Beside some editorial changes the following chapters had been modified:
· Chapter 4.1: BA E-0080, BA R-8312, BA R-8313, BA R-8326: Hazard labelling updated according to Safety Data Sheet
· Chapter 7.1: Hint added regarding clonidine suppression test
· Chapter 9.1: Recovery updated
· Chapter 10: References updated
These revisions will be effective with the IFU versions 21.0 (please refer to the attachments) and with lot numbers 230707.
Please inform everyone who might be affected by these changes.

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