ED-FBGP100M

The DIASTAT™ Anti-ß₂-glycoprotein 1 IgM (ß₂-GP1 IgM) test is a semi-quantitative enzyme-linked immunosorbent assay (ELISA) for the detection of the IgM class of autoantibodies specific for ß₂-GP1 antigen in human serum or sodium citrate, EDTA (K2) and lithium heparin anti-coagulated plasma. It is intended to aid in the assessment of thrombotic risk in patients with autoimmune disease associated with thrombotic disorders such as primary anti-phospholipid syndrome or secondary to systemic lupus erythematosus. It is not definitive in isolation. Autoantibody levels represent one parameter in a multicriterion diagnostic process.

References:

McNally T, Mackie IJ, et al. Blood Coagulation and Fibrinolysis, 6, 411-416, 1995.

McNally T, Mackie IJ, et al. Thrombosis & Haemostasis, 76, 220-225, 1996.

Matsuura E and Koike T. Autoantibodies, Eds. Peter JB and Shoenfeld Y, Elsevier, Amsterdam, 109-114, 1996.

Khamashta MA and Hughes GRV. Autoantibodies, Eds. Peter JB and Shoenfeld Y, Elsevier, Amsterdam, 624-629, 1996.br>
Voss A, Jacobsen S et al. Lupus 2001; 10 (8), 533-538.