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Chromogenic assay measuring Antithrombin III activity in human plasma.Antithrombin III is an inhibitor of plasma serine proteases. An important function of Antithrombin III is the inhibition of thrombin activity. Normally the rate of thrombin inhibition by Antithrombin III is slow; however, the rate..
A two-stage chromogenic assay which measures unfractionated heparin in human plasma by measurement of Factor IIa (thrombin) activity.The inhibitory effect of antithrombin III (ATIII) on Factor IIa (thrombin), Factor Xa and other coagulation serine proteases in plasma is increased several-thousand fo..
A three-stage chromogenic assay for the quantitative determination of unfractionated and low molecular weight heparins in human plasma by measurement of Factor Xa inhibition.The inhibitory effect of antithrombin III (ATIII) on Factor IIa (thrombin), Factor Xa (fXa) and other coagulation serine prote..
A chromogenic assay which measures plasminogen in human plasma.The basis of the assay is the formation of a complex between plasminogen and streptokinase in the presence of excess streptokinase. This plasminogen-streptokinase complex possesses plasmin activity that can be measured using the plasmin ..
A chromogenic assay which measures tissue factor (TF) procoagulant activity in human plasma and cell lysates.TF is a membrane-bound glycoprotein that serves as both the receptor and cofactor for Factor VII (fVII) and Factor VIIa (fVIIa) in initiating cell surface procoagulant activity. TF is absent ..
A three stage chromogenic assay which measures active Tissue Factor Pathway Inhibitor (TFPI) in plasma where TFPI exhibits an inhibitory effect on the tissue factor/fVIIa complex (TF/fVIIa).After incubation of test samples with TF/fVIIa and fX, the residual activity of the TF/fVIIa complex is measur..
Measures Protein C activity in human plasma via an end-point clotting assay.
Protein C is a Vitamin K dependent anticoagulant protein that normally circulates as an inactive zymogen. After activation, Protein C inactivates Factors V and VIII, thus prolonging the clotting time.
The assay uses P..
ACTICLOT® dPT™ is a dilute Prothrombin Time (dPT) test for screening and confirming the presence of phospholipid-dependent LA autoantibodies in plasma.Clinical studies show that a dPT test is an effective LA coagulation assay that identifies LA not detected by other tests, such as a Lupus-sensitive ..
The ACTICLOT® Protein C Resistance assay is a plasma based functional assay for the determination of resistance to activated protein C caused by the factor V Leiden mutation (FV:Q506). Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. O..
Control plasmas for confirmation of factor V Leiden mutation (FV:Q506) to be used with ACTICLOT® Activated Protein C Resistance Assay. Controls contain pooled plasmas of donors with either heterozygous FV:Q506 mutation or normal wild-type pattern. The genetic type of each blood donor has been checke..
A functional clotting assay for the quantitative determination of Protein S activity in human plasma.Protein S is a Vitamin K dependent protein primarily synthesized in the liver, but also in the endothelium and possibly in megakaryocytes. It functions as a cofactor for activated Protein C in the in..
A FRET-based assay for the measurement of ADAMTS13 activity in human plasma.ADAMTS13 is a metalloproteinase that cleaves ultra large (UL) vWF multimers within the A2 region of vWF. Studies have shown that low levels of ADAMTS13 activity are associated with Thrombotic Thrombocytopenia Purpura (TTP), ..
Measures cholesteryl ester transfer protein (CETP) in human serum and plasma. Clinical evidence suggests that coronary artery calcification as well as intima media thickness is positively related to plasma cholesteryl ester transfer, and that high plasma CETP concentration is associated with increas..
A rapid immunoagglutination assay using latex beads coupled with a highly specific monoclonal antibody (DD3B6/22).
Cross linked fibrin degradation product (XL-FDP) present in a plasma sample binds to the coated latex beads, which results in visible agglutination occurring when the concentration i..
DVVconfirm® is the high phospholipid reagent used in conjunction with DVVtest® (REFs 810 & 825) to confirm the presence of LA in plasma. DVVconfirm® is formulated with Russell’s Viper Venom and a high concentration of phospholipids.The clotting time of a plasma containing LA should be significan..