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Measures human urokinase-type plasminogen activator (uPA) in tissue extracts, plasma and cell culture supernatant.Single chain uPA (sc-uPA, pro-uPA) and HMW-uPA forms of urokinase-type plasminogen activator are recognized by the assay, as are receptor-bound uPA and uPA complexed with PAI-1 and PAI-2..
Measures vWF activity in human plasma by making use of a monoclonal antibody that recognizes a functional epitope of the vWF molecule.vWF functions as a carrier protein for Factor VIII, the coagulation protein absent in Hemophilia A. It promotes platelet adhesion to damaged endothelium and participa..
Measures vWF antigen in human plasma.vWF functions as a carrier protein for Factor VIII, the coagulation protein absent in Hemophilia A. It promotes platelet adhesion to damaged endothelium and participates in the platelet-to-platelet cohesion necessary for thrombus formation. Together with fibronec..
Measures human Annexin V in plasma, platelet and blood cell concentrates and other biological fluid or cell culture supernatant in which Annexin V may be present. This assay recognizes both native and recombinant Annexin. For research use only.
Measures D-dimer, cross linked fibrin degradation product (XL-FDP), in human plasma.Elevated XL-FDP levels indicate reactive fibrinolysis and are found in a number of arterial and venous occlusive disease states, including acute Myocardial Infarction (MI), Deep Vein Thrombosis (DVT), Pulmonary Embol..
A competitive assay which measures human Fibrinopeptide A (FPA) on bentonite absorbed human plasma.FPA is cleaved from the amino terminus of fibrinogen A-alpha chains by thrombin. Elevated blood levels of FPA are indicative of excess thrombin activity and are found in various clinical states such as..
Measures Free Protein S in human plasma.Protein S is a Vitamin K dependent glycoprotein synthesized in the liver. In normal human plasma, Protein S is present in two forms: Free Protein S (40% of total Protein S concentration) and Protein S complexed with C4b binding protein (C4b-BP). Only Free Prot..
Measures Platelet Factor 4 (PF4) in platelet depleted human plasma.PF4 is released from activated platelet alpha granules upon platelet activation. PF4 possesses a powerful anti-heparin activity as it binds to heparin, forming a stochiometric complex. Elevated levels of PF4 are observed in various s..
Measures TAFI antigen in human plasma.Thrombin Activatable Fibrinolytic Inhibitor (TAFI), also known as plasma procarboxypeptidase U and procarboxypeptidase B, is converted to its active form (TAFIa) by the thrombin/thrombomodulin complex. TAFIa possesses a preference for cleaving lysine and arginin..
KALLISTOP™ a 4-amidinoanilide derivative of phenyl-2-aminobutyric acid is a relatively selective inhibitor of plasma kallikrein (PK). The inhibitory effect depends on the pH-value. It is increased below pH 7.0 and is decreased above pH 8.0.